VO-OHpic trihydrate, >=98% (HPLC), solid

Code: V8639-10MG D2-231

Not available outside of the UK & Ireland.

Application

VO-OHpic trihydrate has been used in studying the role of phosphatase and tensin homolog (PTEN) in polycomb repressive complex 2 (PRC2)-mediated apoptosis. It als...


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Your Price
$316.54 10MG

Not available outside of the UK & Ireland.

Application

VO-OHpic trihydrate has been used in studying the role of phosphatase and tensin homolog (PTEN) in polycomb repressive complex 2 (PRC2)-mediated apoptosis. It also has been used as a PTEN inhibitor to study the neuroprotective effect of melatonin in amyloid beta (Aβ)-induced neurotoxicity via PTEN pathway.

Biochem/physiol Actions

VO-OHpic trihydrate is a PTEN (phosphatase and tensin homologue deleted on chromosome 10) inhibitor.

General description

VO-OHpic is a vanadium complex. VO-OHpic might act as a possible pro-senescence anti-cancer drug for treating cancers with reduced phosphatase and tensin homolog (PTEN) expression. It blocks cell viability, cell proliferation, colony formation and induced senescence-associated β-galactosidase activity in Hep3B cells.

Packaging

10 mg in glass bottle

assay≥98% (HPLC)
colorgray
formsolid
InChI keyQVBVJWFAUFEGMT-UHFFFAOYSA-K
InChI1S/2C6H5NO3.4H2O.O.V.H/c2*8-4-2-1-3-7-5(4)6(9)10;;;;;;;/h2*1-3,8H,(H,9,10);4*1H2;;;/q;;;;;;;+3;/p-3
Quality Level100
SMILES stringO.O.O.O.Oc1cccnc1C(=O)O[VH]2(=O)OC(=O)c3cccnc3O2
solubilityDMSO: >10 mg/mL
storage temp.−20°C
Cas Number476310-60-8
This product has met the following criteria to qualify for the following awards:



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