SR 142948A, > = 98 %(HPLC)

Name: SR 142948A, > = 98 %(HPLC)
Brand: SIGMA-ALDRICH
SKU: sml0015-5mg
Price: 222.74 USD

Code: sml0015-5mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

SR 142948A was used to study the role of neurotensin signaling in intracellular alkanization and expression of IL-8 in human pancreatic cancer cells.

Votre prix

$222.74 5MG

Abandonné

PRÉSENTATION
SPÉCIFICATIONS
DOCUMENTS
ATTRIBUTS

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

SR 142948A was used to study the role of neurotensin signaling in intracellular alkanization and expression of IL-8 in human pancreatic cancer cells.

Biochem/physiol Actions

SR 142948A is a non-peptide Neurotensin receptor antagonist

SR 142948A is a potent neurotensin receptor antagonist that affects the expression of c-Fos and has properties of antipsychotic agent. It blocks hypothermia and analgesia induced by neurotensin. It blocks the increase in the concentration of Ca⁺² induced by the activation of phospholipase C in CHO cell model.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is featured on the Neurotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI key	CUYNEHGBVHUQQW-BVJGGMLGSA-N
InChI	1S/C39H51N5O6.ClH/c1-23(2)29-21-26(37(46)43(5)15-9-14-42(3)4)12-13-31(29)44-32(35-33(49-6)10-8-11-34(35)50-7)22-30(41-44)36(45)40-39(38(47)48)27-17-24-16-25(19-27)20-28(39)18-24;/h8,10-13,21-25,27-28H,9,14-20H2,1-7H3,(H,40,45)(H,47,48);1H/t24-,25+,27-,28+,39?;
originator	Sanofi Aventis
Quality Level	100
SMILES string	Cl.COc1cccc(OC)c1-c2cc(nn2-c3ccc(cc3C(C)C)C(=O)N(C)CCCN(C)C)C(=O)NC4([C@@H]5C[C@H]6C[C@@H](C5)C[C@@H]4C6)C(O)=O
solubility	H₂O: ≥2 mg/mL at warmed to 60 °C
storage temp.	2-8°C

Safety Data Sheet for SML0015-5MG
Certificat d'analyse Sigma

Cas Number

184162-21-8

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

SR 142948A, > = 98 %(HPLC)

À PROPOS DE NOUS

INFORMATIONS

FORMULAIRES

NOUS APPELER