Fumonisine B2 de Fusarium moniliforme, inhibiteur de la sphingosine n-acyltransférase

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Fumonisin B₂ (FB₂) from Fusarium moniliforme has been used:as a standard for the detection of FB₂ by high performance liquid chromatography (HPLC) in corn based food productsused as standard in the determination of fumonisin B1 and B2 in corn and corn-based products by high-performance liquid chromatographyas a standard in the determination of mycotoxins by HPLC

Biochem/physiol Actions

Inhibitor of sphingosine N-acyltransferase. Blocks the formation of ceramide from sphingosine.

General description

Mycotoxin originally isolated from Fusarium sp, which grows on corn. Produces neural tube defects and craniofacial abnormalities in fetuses. Many strains of Aspergillus niger growing naturally on grapes are capable of producing fumonisin B₂, so it is now a concern for human consumption of grapes, raisins, and wine.

Fumonisin B₂ (FB₂) is a diester of tricarballylic acid and polyhydric alcohols.. Fumonisins B₂ (FB₂) does not have one or more hydroxyl groups at the C5 or C10 positions.

Packaging

1 mg in glass bottle

10 mg in glass insert