Fluorescein isothiocyanate-dextran, average Mw 70,000

Not available outside of the UK & Ireland.

Application

Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.

Fluorescein isothiocyanate–dextran has an application of cell analysis, Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals. FITC-dextrans are primary source of studying permeability and transport in cells and tissues and can also be a tool for permeability studies of other materials.

General description

Fluorescein isothiocyanate–dextran is an anionic fluorescent probe. The carboxyl group provides the negative charge, which improves the overall permeability of the molecule. It is supplied as a yellow powder that is freely soluble in water and electrolyte solutions. Fluorescein isothiocyanate–dextran is insoluble in most organic samples such as ethanol, methanol, acetone, and chloroform., however, it dissolves in DMSO, formamide, and a few other polar organic solvents.