Lopinavir

Code: sml1222-10mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Lopinavir has been used as a ZMPSTE24 and human immunodeficiency virus protease inhibitor.

Biochem/physiol Actions

Lopinavir is an an...


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$37.29 10MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Lopinavir has been used as a ZMPSTE24 and human immunodeficiency virus protease inhibitor.

Biochem/physiol Actions

Lopinavir is an antiviral HIV Protease Inhibitor. Lopinavir has insufficient bioavailability alone, so it is used in therapy in combination with Ritonavir, a HIV protease inhibitor, which inhibits cytochrome P450-3A4 (CYP3A4), a liver enzyme that normally metabolizes protease inhibitors. Lopinavir also has an ability to inhibit ZMPSTE24 (zinc metallopeptidase STE24).

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyKJHKTHWMRKYKJE-SUGCFTRWSA-N
InChI1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
optical activity[α]/D -20 to -27°, c = 0.4 in methanol
Quality Level100
solubilityDMSO: 20 mg/mL, clear
storage temp.−20°C
Cas Number192725-17-0
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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