Hydrochlorure AZD - 7762 ,>= 98% (HPLC)

Code: sml0350-5mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

AZD-7762 hydrochloride has been used:as a checkpoint kinase 1 and 2 (CHK1/2) inhibitor to study its effect on the efficiency of non-homologous end-joining (NHEJ) ...


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Votre prix
$148.08 5MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

AZD-7762 hydrochloride has been used:as a checkpoint kinase 1 and 2 (CHK1/2) inhibitor to study its effect on the efficiency of non-homologous end-joining (NHEJ) repair in breast cancer cell linesas a CHK1 inhibitor to serve as a positive control for replication stress in the assessment of fork restart eventsas a CHK1/2 inhibitor to study its effects on DNA lesions during mice zygote development

Biochem/physiol Actions

AZD-7762 is a potent, ATP-competitive inhibitor of Chk1 and Chk2 that enhanced cytotoxicity DNA-damaging agents.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to light brown
formpowder
InChI keyWFZBLOIXZRZEDG-YDALLXLXSA-N
InChI1S/C17H19FN4O2S.ClH/c18-11-4-1-3-10(7-11)14-8-13(22-17(19)24)15(25-14)16(23)21-12-5-2-6-20-9-12;/h1,3-4,7-8,12,20H,2,5-6,9H2,(H,21,23)(H3,19,22,24);1H/t12-;/m0./s1
Quality Level100
SMILES stringCl.NC(=O)Nc1cc(sc1C(=O)N[C@H]2CCCNC2)-c3cccc(F)c3
solubilityDMSO: 15 mg/mL, clear
storage conditiondesiccated
storage temp.−20°C
Cas Number1246094-78-9
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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