(-)-Scopolamine methyl bromide, >=98% (HPLC), powder

Name: (-)-Scopolamine methyl bromide, >=98% (HPLC), powder
Brand: SIGMA-ALDRICH
SKU: s8502-1g
Price: 94.64 USD

Code: s8502-1g D2-231

Not available outside of the UK & Ireland.

Application

(−)-Scopolamine methyl bromide was administered to rats to inhibit the peripheral cholinergic effects induced by pilocarpine.^10,11

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Not available outside of the UK & Ireland.
Application
(−)-Scopolamine methyl bromide was administered to rats to inhibit the peripheral cholinergic effects induced by pilocarpine.^10,11
Biochem/physiol Actions
Scopolamine is an anti-muscarinic and cholinolytic alkaloid that inhibits parasympathetic-cholinergic system.⁷ The central effects include hallucinations, disorientation, restlessness and euphoria.⁸ Scopolamine disturb the stimulus detection performance in rats by interfering with the reticular cholinergic pathways.⁹
Competitive muscarinic acetylcholine receptor antagonist.
Caution
Shelf-life of the powder is at least five years when stored at room temperature.
Packaging
1, 5 g in poly bottle

assay ≥98% (HPLC)
color white
form powder
Gene Information human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)
InChI key CXYRUNPLKGGUJF-RAFJPFSSSA-M
InChI 1S/C18H24NO4.BrH/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11;/h3-7,12-17,20H,8-10H2,1-2H3;1H/q+1;/p-1/t12-,13-,14-,15+,16-,17+;/m1./s1
optical activity [α]25/D −25°, c = 5 in H₂O(lit.)
Quality Level 200
SMILES string [Br-].[H][C@]12C[C@@H](C[C@]([H])([C@@]3([H])O[C@@]13[H])[N+]2(C)C)OC(=O)[C@H](CO)c4ccccc4
solubility H₂O: 50 mg/mL

Safety Data Sheet
Safety Data Sheet for S8502-1G
Certificate of Analysis
Sigma Certificate of Analysis

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Cas Number 155-41-9

This product has met the following criteria to qualify for the following awards:

(-)-Scopolamine methyl bromide, >=98% (HPLC), powder

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assay	≥98% (HPLC)
color	white
form	powder
Gene Information	human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)
InChI key	CXYRUNPLKGGUJF-RAFJPFSSSA-M
InChI	1S/C18H24NO4.BrH/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11;/h3-7,12-17,20H,8-10H2,1-2H3;1H/q+1;/p-1/t12-,13-,14-,15+,16-,17+;/m1./s1
optical activity	[α]25/D −25°, c = 5 in H₂O(lit.)
Quality Level	200
SMILES string	[Br-].[H][C@]12C[C@@H](C[C@]([H])([C@@]3([H])O[C@@]13[H])[N+]2(C)C)OC(=O)[C@H](CO)c4ccccc4
solubility	H₂O: 50 mg/mL