GW0742, > = 98% ( HPLC), solide

Code: g3295-1mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

GW0742 is a highly selective PPARδ agonist. EC50 = 1 nM vs 1 µM and 2 µM for PPARα and PPARγ, respectively.

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$180.39 1MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

GW0742 is a highly selective PPARδ agonist. EC50 = 1 nM vs 1 µM and 2 µM for PPARα and PPARγ, respectively.

Features and Benefits

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from GlaxoSmithKline

Packaging

1, 5 mg in glass bottle

assay≥98% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... PPARA(5465), PPARD(5467), PPARG(5468)
InChI keyHWVNEWGKWRGSRK-UHFFFAOYSA-N
InChI1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)
mp134.5-135.5 °C
originatorGlaxoSmithKline
Quality Level100
SMILES stringCc1cc(SCc2sc(nc2C)-c3ccc(c(F)c3)C(F)(F)F)ccc1OCC(O)=O
solubilityDMSO: >5 mg/mL, H2O: insoluble
storage temp.2-8°C
Cas Number317318-84-6
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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