Fenvalerate, >=97 %

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Fenvalerate has been used to study the effect of Fen exposure on reproductive functions.

Biochem/physiol Actions

Fenvalerate is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B). This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell.

Fenvalerate has good insecticidal potential and is less toxic to animals. It might cause endocrine disruption and reproductive dysfunction in humans. Metabolism of fenvalerate includes oxidation, ester cleavage and conjugation reaction. It is stable at pH 5 and 7, while it gets hydrolyzed at pH 9. In rat models it is found to hinder the action of mitochondrial enzymes.

Type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B).

General description

Fenvalerate an ester molecule, exists in four stereoisomers with two chiral centers.

Preparation Note

Fenvalerate has been reported to be soluble in DMSO, ethanol, and acetone.