S )-(-)-Bay K8644, >= 98%( HPLC ), solide

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

(S)-(-)-Bay K8644 has been used as a L-type calcium channel (LTCC) agonist in the suprachiasmatic nucleus (SCN) slices. It has also been used as a LTCC agonist to induce arrhythmiain rats.

Biochem/physiol Actions

(S)-(-)-Bay K8644 enhances Ca²⁺ current, whereas the (+)-Bay K 8644 is a weak Ca²⁺ channel antagonist. Bay K 8644 is lipophilic and it effectively scavenges superoxide anions.

Features and Benefits

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

General description

(S)-(-)-Bay K8644, a dihydropyridine compound is a Ca²⁺channel activator. It is an enantiomer of Bay K 8644.

Legal Information

Manufactured and sold with the permission of Bayer AG.

Packaging

1, 5 mg in glass bottle