Atosiban, >= 98%( HPLC )

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Atosiban has been used:as an oxytocin receptor antagonistin the calcium mobilization assay for Z factor determination in uterine myometrium (UT-myo cells) and as a therapeutic agent to inhibit preterm laborto inhibit the activation of oxytocin-receptor-expressing neurons in the parabrachial nucleus of mice (Oxtr^PBN)

Biochem/physiol Actions

Atosiban efficiently prevent preterm uterine contractions without any major cardiovascular, pulmonary or central nervous system side effects. It has potential to treat preterm labour.

Atosiban is a peptide oxytocin receptor antagonist.

Features and Benefits

This compound was developed by Ferring. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

10 mg in glass bottle

Reconstitution

Reconstitute in deionized water at not less than 100 µg/mL, which can then be diluted into aqueous vehicle of choice. Solutions may be stored at 2-8 °C for up to seven days. For extended storage, add a carrier protein of 0.1% human serum albumin or bovine serum albumin and freeze in working aliquots at −20 °C.