Anticorps Monoclonal Anti - HLA - e produit dans la souris, clone MEM - e / 08, immunoglobulin purifié, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 4 µg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Features and Benefits

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General description

The antibody MEM-E/08 recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results revealed that antibody is remarkably specific for HLA-E, only with weak cross-reactivity with following classical MHC Class I molecules (MHC Class Ia): HLA-A24, -B7, -B27, -B51, -B54, -C7.

Immunogen

Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.