Anti-calorique, anticorps C - Terminal produit en lapin, environ 1 mg / mL, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

CANX (calnexin) participates in protein folding and quality control. It is responsible for glycan-independent interaction and retention of mutated Gas3/PMP22 (growth arrest-specific protein 3/peripheral myelin protein 22) proteins involved in Charcot-Marie-Tooth 1A and Dejerine Sottas syndrome.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Anti-Calnexin Antibody detects endogenous levels of total Calnexin protein.

CANX (calnexin) is an endoplasmic reticulum (ER) chaperone. It has a molecular weight of 67kDa. It is a type I transmembrane protein and is located on human chromosome 5q35.

Immunogen

The antiserum was produced against synthesized peptide derived from human Calnexin.Immunogen Range: 543-592

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.