Anti-Integrin beta3, C-Terminal antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Mutations in ITGB3 (integrin subunit β 3) results in Glanzmann thrombasthenia (GT). It plays a major role in the movement and attack of colorectal cancer cells promoted by reactive oxygen species.

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General description

ITGB3 (integrin subunit β 3) codes for integrin αIIbβ3. It is located on human chromosome 17q21.31-32.

Anti-Integrin β3 Antibody detects endogenous levels of total Integrin β3 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human Integrin beta3.Immunogen Range: 739-788

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.