Monoclonal Anti-POLD1 antibody produced in mouse,

Not available outside of the UK & Ireland.

Application

For WB: Use at a concentration of 1:1,000. Predicted molecular weight: 130 kDa. Optimal dilutions/concentrations should be determined by the reseracher.

Biochem/physiol Actions

DNA polymerase d (delta) functions in DNA replication and DNA repair. It also possesses 3′ to 5′ exonuclease activity. In leading strand synthesis it requires the processivity factor, PCNA. It is also possibly involved in the completion of DNA synthesis during Okazaki fragment elongation following the initiation of synthesis by the DNA polymerase a/primase complex

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Immunogen

Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.

Physical form

Phosphate-buffered saline, pH 7.2, containing no preservatives