Non disponible en dehors du Royaume-Uni et de l'Irlande
General description
ZPK, a member of the Ser/Thr protein kinase family (MAP kinase kinase kinase subfamily), may be an activator of the JNK/SAPK pathway. It phosphorylates beta-casein, histone 1 and myelin basic protein in vitro, and interacts with MBIP through the leucine-zipper motif. ZPK is highly expressed in brain and kidney. It is phosphorylated in cytosol under basal conditions and dephosphorylated when membrane-associated.
Immunogen
ZPK (530-565)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ZPK.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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