Non disponible en dehors du Royaume-Uni et de l'Irlande
General description
CDCA8 is a component of the chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle. The CPC complex, a key regulator of mitosis, has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 may be required to direct the CPC to centromeric DNA.
Immunogen
CDCA8 (NP_060571, 120-154)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human CDCA8.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :