Anticorps Anti - VENTX produit dans la souris, immunoglobulin purifiée, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Vent homeobox(VENTX) regulates proliferation and differentiation of hematopoietic cells.VENTX acts as a tumor suppressor and plays an important role in proinflammatory activation.Dysregulation of VENTX may contribute to pathogenesis of autoimmune diseases.

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General description

This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas (provided by RefSeq). Vent homeobox (VENTX) is a human homeobox transcription factor. VENTXis majorly expressed in human myeloid cells. VENTX gene is located on human chromosome 10q26.3.

Immunogen

VENTX (NP_055283.1, 1 a.a. ~ 258 a.a) full-length human protein.SequenceMRLSSSPPRGPQQLSSFGSVDWLSQSSCSGPTHTPRPADFSLGSLPGPGQTSGAREPPQAVSIKEAAGSSNLPAPERTMAGLSKEPNTLRAPRVRTAFTMEQVRTLEGVFQHHQYLSPLERKRLAREMQLSEVQIKTWFQNRRMKHKRQMQDPQLHSPFSGSLHAPPAFYSTSSGLANGLQLLCPWAPLSGPQALMLPPGSFWGLCQVAQEALASAGASCCGQPLASHPPTPGRPSLGPALSTGPRGLCAMPQTGDAF

Physical form

Solution in phosphate buffered saline, pH 7.4