ÉRUPTION

Code: SML2231-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Erasin (Erlotinib-resistance antagonizing STAT3 inhibitor) is a selective inhibitor of STAT3 with selectivity over STAT5 and STAT1 in cell-based assay...


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$85.75 5MG
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Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Erasin (Erlotinib-resistance antagonizing STAT3 inhibitor) is a selective inhibitor of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays. It was shown to increase the apoptotic rate of HCC-827 cells with acquired resistance against Erlotinib in addition to increasing the apoptotic rate of cultured NSCLC cells in a STAT3-dependent manner.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringO=C1C(/C=N/NC(C2=CC=CN=C2)=O)=COC3=CC=C(C(C)(C)C)C=C31
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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