X-34

Code: SML1954-25MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

X-34 is a fluorescent, amyloid-specific dye. It binds at a different site than Pittsburgh Compound B and is a highly fluorescent marker for beta-sheet...


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$596.08 25MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

X-34 is a fluorescent, amyloid-specific dye. It binds at a different site than Pittsburgh Compound B and is a highly fluorescent marker for beta-sheet structures.

Fluorescent, amyloid-specific dye

X-34 (1,4-bis(3-carboxy-4-hydroxyphenylethenyl)-benzene) is one among the small-molecule γ-secretase modulators (GSMs) involved in lowering Aβ42 levels (the 42-residue isoform of the amyloid-β peptide). X-34 has also been used to visualize intracellular immunoreactive deposits with classic amyloid fibrillar ultrastructure in living transgenic Caenorhabditis elegans animals. It is also used as a histochemical stain for determining pathological changes in Alzheimer′s disease (AD).

assay≥90% (HPLC)
colorwhite to beige
formpowder
Quality Level100
SMILES stringOC(C=C1)=C(C(O)=O)C=C1C=CC2=CC=C(C=CC3=CC=C(O)C(C(O)=O)=C3)C=C2
solubilityDMSO: 2.0 mg/mL, clear
storage temp.2-8°C
Cas Number215294-98-7
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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