AZ3146

Code: SML1427-25MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

AZ3146 is a potent and specific inhibitor of monopolar spindle 1 kinase (Mps1; IC50 = 35 nM), an important regulator of Spindle Assembly Ch...


en savoir plus

Votre prix
$641.07 25MG
Abandonné

PRÉSENTATION

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

AZ3146 is a potent and specific inhibitor of monopolar spindle 1 kinase (Mps1; IC50 = 35 nM), an important regulator of Spindle Assembly Checkpoint (SAC). AZ3146 treated HeLa cells override SAC, and quickly enter mitosis, with a reduced mitosis completion time of 32 minutes. 50% of treated cells entered anaphase without complete chromosomal alignment.

Packaging

5, 25 mg in glass bottle

SPÉCIFICATIONS
assay≥98% (HPLC)
colorwhite to light brown
formpowder
InChI keyYUKWVHPTFRQHMF-UHFFFAOYSA-N
InChI1S/C24H32N6O3/c1-28-12-10-17(11-13-28)33-18-8-9-19(21(14-18)32-3)26-23-25-15-20-22(27-23)30(24(31)29(20)2)16-6-4-5-7-16/h8-9,14-17H,4-7,10-13H2,1-3H3,(H,25,26,27)
Quality Level100
SMILES stringCN1CCC(OC2=CC(OC)=C(NC3=NC=C4C(N(C5CCCC5)C(N4C)=O)=N3)C=C2)CC1
solubilityDMSO: 2 mg/mL, clear (warmed)
storage temp.2-8°C
DOCUMENTS
PLAGE
ATTRIBUTS
Cas Number1124329-14-1
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN

GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.