VU591, > = 98 %(HPLC)

Code: SML0077-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

VU591 may be used in cell signaling studies.

Biochem/physiol Actions

VU591 is a Potassium Inwardly-Rectifying Channel (KCNJ1 or ROMK)...


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Votre prix
$128.56 5MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

VU591 may be used in cell signaling studies.

Biochem/physiol Actions

VU591 is a Potassium Inwardly-Rectifying Channel (KCNJ1 or ROMK) specific inhibitor (IC50 = 240 nM) that is closely related to VU590. Unlike VU590, VU591 does not inhibit Kir7.1. The compound has a modest effect on Kir6.2/SUR1, causing 17% inhibition at 10 uM.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to tan
formpowder
Gene Informationhuman ... KCNJ1(3758)
InChI keyZQPXNYLXYNRFNP-UHFFFAOYSA-N
InChI1S/C16H12N6O5/c23-21(24)9-1-3-11-13(5-9)19-15(17-11)7-27-8-16-18-12-4-2-10(22(25)26)6-14(12)20-16/h1-6H,7-8H2,(H,17,19)(H,18,20)
Quality Level100
SMILES string[O-][N+](=O)c1ccc2nc(COCc3nc4ccc(cc4[nH]3)[N+]([O-])=O)[nH]c2c1
solubilityDMSO: ≥12 mg/mL
storage temp.2-8°C
Cas Number1222810-74-3
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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