Dihydrochlorure de Pipamperone, environ 0,99% (HPLC) , poudre

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Pipamperone dihydrochloride may be used: as an internal standard in liquid chromatography with coulometric detectionas an antipsychotic drugs to test its interaction with human ether-a-go-go-related gene (hERG) channelas an internal standard to spike human colostrum samples for reversed phase liquid chromatography- ultraviolet (LC-UV) analysis

Biochem/physiol Actions

Pipamperone, a butyrophenone derivative is a pharmacological chaperone and is a membrane-permeable dopamine receptor D4 (DRD4) antagonist. The affinity of pipamperone is higher for DRD4 and 5-hydroxytryptamine 2A receptor (5-HT2A) in comparison with DRD2. It may be useful therapeutic in treating behavioral disorders and psychomotor agitation symptoms.

D₂ dopamine receptor antagonist; 5-HT₂ serotonin receptor antagonist; antipsychotic.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

100 mg in poly bottle