Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
LOPAC® 1280 - Small Scale has been used: in sprouting assay to screen potential lymphangiogenic inhibitors and the signaling pathways involved in lymphangiogenesisfor identification of neuroactive compounds by measuring spontaneous activity within single zebrafish embryos by high-content screening assayfor high-throughput Screen for ectonucleoside triphosphate diphosphohydrolase-1 (ENTPD1; also known as CD39) and ecto-5′-nucleotidase (CD73) inhibitors
Features and Benefits
Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience: Apoptosis G Proteins & Cyclic Nucleotides Gene Regulation & Expression Ion Channels Lipid Signaling Multi-Drug Resistance Neurotransmission Phosphorylation
SDFile provided to construct a database containing: Structure Primary Name Secondary Name Pharmacological Activity Product Number Rack Position
General description
Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (25 µl at 10 mM in DMSO in archival storage racks).
LOPAC® 1280 is an extensively used library of pharmacologically active compounds. This library includes 1,280 marketed drugs, failed development candidates, and small molecules with well-characterized activities. LOPAC 1280 spans a broad molecular weight range, exhibits multiple mechanisms of action and interacts with a variety of biological receptors.
Legal Information
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Other Notes
For sale inside of the U.S. only. Customers outside the US should refer to Product Code LO4200.
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :