1-( 3 5-difluorophéyl)sulfonyl) bicyclo[1,0]butane

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

The following "spring-loaded" electrophile is a convenient reagent for the installation of cyclobutane to primary and secondary amines. This product is one of several synthetically useful reagents reported by Baran and coworkers on strain-release amination.

General description

1-((3,5-Difluorophenyl)sulfonyl)bicyclo[1.1.0]butane can be used as a cyclobutylation agent to introduce bicyclobutane group onto a variety of amines and thiols without affecting other functional groups.

Packaging

500 mg in glass bottle