2-(3-MAIS-3-YNYL - 3H - diazirine-3 - YL)-ETHAN

Code: 900863-50mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, a...


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Votre prix
$420.01 EACH

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifunctional Probe Building BlocksFluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone DeacetylasesIn Situ Proteome Profiling and Bioimaging Applications of Small-Molecule Affinity-Based Probes Derived From DOT1L InhibitorsReversible inhibitors arrest ClpP in a defined conformational state that can be revoked by ClpX associationDesign and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

assay≥95%
density1.08 g/mL
formliquid
Quality Level100
SMILES stringOCCC1(N=N1)CCC#C
storage temp.−20°C
Cas Number1450754-41-2
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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