7-DEHYDRODESMOSTEROL

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

7-dehydrodesmosterol has been used as an internal oxysterol standard in ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).

Biochem/physiol Actions

7-dehydrodesmosterol (7-DHD) levels are higher during fetal development and increases with aging. Elevated levels of 7-DHD is associated with Smith-Lemli-Opitz syndrome mouse model. Reduced levels of 7-DHD is observed in shiverer and quaking disorder.

General description

7-dehydrodesmosterol (7-DHD) is synthesized via the Bloch pathway. 7-DHD serves as a desmosterol synthesis precursor and the enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes this step.

Packaging

5 mL Amber Glass Screw Cap Vial (700138P-1mg)