IL-2R # antagoniste 1 pc x 5 mg

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Target IC₅₀: 3 µM against IL-2/IL-2Rα interaction

Cell permeable: no

Reversible: no

Primary TargetInhibitor of the IL-2/IL-2Rα interaction

Product does not compete with ATP.

General description

A non-peptidyl acylphenylalanine compound that binds to IL-2 and acts as a competitive inhibitor of the IL-2/IL-2Rα interaction (IC₅₀ = 3 µM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Emerson, S.D., et al. 2003. Protein Science12, 811.Tilley, J.W., et al. 1997. J. Am. Chem. Soc.119, 7589.

Packaging

Packaged under inert gas

5 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Warning

Toxicity: Standard Handling (A)