Non disponible en dehors du Royaume-Uni et de l'Irlande
General description
A cell-permeable pyridopyrimidinyl urea compound that acts a potent, ATP-competitive inhibitor of FGFR (IC50 = 60 nM using FGFR1) with excellent selectivity over PDGFRβ, EGFR, insulin receptor, and c-Src (IC50 >50 µM).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Panek, R.L., et al. 1998. J. Pharm. Exp. Ther.286, 569.Hamby, J.M., et al. 1997. J. Med. Chem.40, 2296.
Packaging
Packaged under inert gas
5 mg in Plastic ampoule
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Warning
Toxicity: Irritant (B)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :