1;2-Dioctanoyl-sn-glycerol

Non disponible en dehors du Royaume-Uni et de l'Irlande

Analysis Note

Single spot by TLC

Biochem/physiol Actions

Reversible: no

Primary TargetProtein kinase C

Cell permeable: yes

General description

Cell-permeable activator of protein kinase C; however, it has lower affinity for PKCa than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.

Cell-permeable activator of protein kinase C (PKC). Exhibits lower affinity for PKC_α than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Ferro, T.J., et al. 1993. Am. J. Physiol. 264, L7.MacEwan, D.J., et al. 1993. Eur. J. Pharmacol. 246, 9.Davis, R.J. 1985. J. Biol. Chem.260, 1562.

Packaging

Packaged under inert gas

10 mg in Plastic ampoule

Reconstitution

Unstable in solution; reconstitute just prior to use.

Warning

Toxicity: Standard Handling (A)