Digues ; sel de désinfectant

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Target IC₅₀: 150 nM inhibiting Cl- uptake in neuroblastoma cells

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetCl- uptake

General description

Binds covalently and irreversibly to the outer surface of human erythrocyte membrane proteins. Inhibits ATP transport into the endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl^- uptake (IC₅₀ = 150 nM) in neuroblastoma cells. Has antiulcerous activity.

Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl^– uptake (IC₅₀ = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Bettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375.Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117.Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659.Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol.15, 207.

Packaging

250 mg in Plastic ampoule

Warning

Toxicity: Irritant (B)