Cilostamide

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Target IC₅₀: 70 nM against PDE III

Reversible: no

Product does not compete with ATP.

Cell permeable: yes

Primary TargetPDE 3

General description

A cell-permeable selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC₅₀ = 70 nM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Verghese, M.W., et al. 1995. J. Pharmacol. Exp. Ther. 272, 1313.Christensen, S.B., and Trophy, T.J. 1994. Ann. Rep. Med. Chem. 29, 185.Tang, K.M., et al. 1994. Eur. J. Pharmacol. 268, 105.

Packaging

10 mg in Plastic ampoule

Reconstitution

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.

Warning

Toxicity: Standard Handling (A)