Peptide inhibiteur Autocamtide-2; myristoysé

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Primary TargetCalmodulin-Dependent Protein Kinase (CaM Kinase)-2

Reversible: no

Product does not compete with ATP.

Target IC₅₀: 40 nM against cam Kinase-2

Cell permeable: yes

General description

This peptide corresponds to AIP (Cat. No. 189480) which has been myristoylated at the N-terminus, enhancing its cell-permeability.

This peptide corresponds to AIP (Cat. No. 189480) which has been myristoylated at the N-terminus, thus enhancing its cell-permeability.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Gailly, P., et al. 1998. Cell Calcium 24, 293.Ishida, A., and Fujisawa, H. 1995. J. Biol. Chem.270, 2163.Ishida, A., et al. 1995. Biochem. Biophys. Res. Commun.212, 806.

Packaging

500 µg in Plastic ampoule

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Sequence

Myr-N-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH

Warning

Toxicity: Standard Handling (A)