Non disponible en dehors du Royaume-Uni et de l'Irlande
General description
A cell-permeable purine nucleoside compound that acts as a highly potent, tight binding transition state analog inhibitor of adenosine deaminase (ADA; Ki= 2.5 pM against partially purified human erythrocytes, and 0.48 to 9.1 nM against rat liver, rat intestine, rat hepatoma and human B cells). Reported to be an immunomodulator and exert selective toxicity towards lymphocytes.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Robak, T. 2007. Cancer Treat. Rev.33, 710.Klohs, W.D. and Kraker, A.J., 1992. Pharmacol. Rev.44, 459.Agarwal, R.P., et al. 1977. Biochem. Pharmacol.26, 359.
Packaging
Packaged under inert gas
10 mg in Glass bottle
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Warning
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :