Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
YIL-781 has been used as a ghrelin receptor (GHSR) antagonist in combination with methanandamide (mAEA) to study its effect on gastric vagal afferent mechanosensitivity.
Biochem/physiol Actions
YIL-781 is a potent antagonist (Ki = 17 nM) of the growth hormone secretagogue receptor (GHS-R1). YIL-781 blocks ghrelin-induced reduction of insulin secretion in rat islets. In vivo, the compound YIL-781 improves glucose tolerance and reduces weight gain.
Packaging
5, 25 mg in glass bottle
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :