Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
PF-06726304 is a selective inhibitor of Histone-lysine N-methyltransferase EZH2 (enhancer of Zeste homolog 2), which catalyzes trimethylation of histone H3 lysine 27 (H3K27) and is amplified and/or overexpressed in several human cancers including breast, prostate and lymphoma. PF-06726304 is a novel structural class of EZH2 inhibitor.
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Sold for research purposes under agreement from Pfizer Inc.
Packaging
5 mg in glass bottle
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