NSCI, >= 97%( HPLC ), solide

Code: n1413-5mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

NSCI has been used as an apoptosis inhibitor to study its effects on caspase 9 activity in cultured tick cells. It has also been used as an apoptosis inhibitor in...


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Votre prix
$182.00 5MG
Abandonné

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

NSCI has been used as an apoptosis inhibitor to study its effects on caspase 9 activity in cultured tick cells. It has also been used as an apoptosis inhibitor in terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assay to study anti-CD3-induced apoptosis in the cluster of differentiation 4 (CD4+) and cluster of differentiation 8 (CD8+) T cells from pleural effusions, mononuclear cells (PEMCs).

Biochem/physiol Actions

1-(4-Methoxybenzyl)-5-[2-(pyridin-3-yl-oxymethyl)pyrrolidine-1-sulfonyl]-1H-indole-2,3-dione (NSCI) is a nonpeptide caspase 3 selective inhibitor.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥97% (HPLC)
formsolid
Gene Informationhuman ... CASP1(834), CASP3(836), CASP6(839), CASP7(840), SUMO1(7341)
InChI keyXDHJBIYJRNFDKS-IBGZPJMESA-N
InChI1S/C26H25N3O6S/c1-34-20-8-6-18(7-9-20)16-28-24-11-10-22(14-23(24)25(30)26(28)31)36(32,33)29-13-3-4-19(29)17-35-21-5-2-12-27-15-21/h2,5-12,14-15,19H,3-4,13,16-17H2,1H3/t19-/m0/s1
Quality Level100
SMILES stringCOc1ccc(CN2C(=O)C(=O)c3cc(ccc23)S(=O)(=O)N4CCC[C@H]4COc5cccnc5)cc1
solubilityDMSO: >10 mg/mL, H2O: insoluble
storage temp.−20°C
Cas Number872254-32-5
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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