TENOFOVIR

Code: sml1795-25mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Tenofovir is a nucleotide analogue reverse transcriptase inhibitor (nRTI) that causes premature termination of DNA transcription. Tenofovir is an anti...


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$674.45 25MG
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Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Tenofovir is a nucleotide analogue reverse transcriptase inhibitor (nRTI) that causes premature termination of DNA transcription. Tenofovir is an antiretroviral used for HIV treatment and prevention.

Tenofovir has a low oral bioavailability. Hence, it is available as a prodrug called tenofovir disoproxil fumarate. Once ingested, tenofovir disoproxil fumarate is hydrolyzed to tenofovir and phosphorylated. This is then incorporated into the viral DNA which leads to chain termination. Tenofovir is also effective against hepatitis B virus.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keySGOIRFVFHAKUTI-ZCFIWIBFSA-N
InChI1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1
optical activity[α]/D -20 to -26°, c = 0.5 in 1 M HCl
Quality Level100
SMILES stringOP(CO[C@H](C)CN1C2=NC=NC(N)=C2N=C1)(O)=O
solubilityH2O: 2 mg/mL, clear (warmed)
storage temp.−20°C
Cas Number147127-20-6
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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