ASP7663

Code: sml1467-25mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1), known to play a role for chemical sensing in the pain pathway. ASP...


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$490.02 25MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1), known to play a role for chemical sensing in the pain pathway. ASP7663 activated human, rat, and mouse TRPA1 receptors with EC50 values of 510, 540, and 500 nM, respectively, and little or no affinity at more than 60 other related receptors, channels and enzymes. ASP7663 enhanced colonic motility and exerted analgesic effects against abdominal pain in mouse models.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorlight orange to dark orange
formpowder
InChI keyRCVZUIGCNAAMIC-UXBLZVDNSA-N
InChI1S/C14H14FNO3/c1-8(2)7-16-13-9(4-3-5-11(13)15)10(14(16)19)6-12(17)18/h3-6,8H,7H2,1-2H3,(H,17,18)/b10-6+
Quality Level100
SMILES stringCC(C)CN(C1=C(F)C=CC=C1/C2=CC(O)=O)C2=O
solubilityDMSO: 25 mg/mL, clear
storage temp.2-8°C
Cas Number1190217-35-6
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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