BOP BENZOTRIAZOLE-1 - YL - OXY - TRIS -(diméthylamino)-HEXAFLUOROPHOSPHATE de PHOSPHONIUM

Non disponible en dehors du Royaume-Uni et de l'Irlande

Analysis Note

Color (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testAssay (HPLC, area%): ≥ 99.0 % (a/a)Solubility (0.6 mmole in 1 ml DMF): clearly soluble

General description

Peptide coupling reagent which suppresses enantiomerization [1-15]. Reduction of carboxylic acids activated with BOP provides a facile route to alcohols [16].

Novabiochem^® recommends the replacement of BOP by PyBOP™(for PyBOP™ please see 851009). The manufacture of BOP, as well as its utilization, involves the use or the formation of hexamethylphosphotriamide, the carcinogenicity and respiratory toxicity of which has been the subject of numerous reports.

The product number for this product was previously 01-62-0001.

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Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 01-62-0001