Scopoletin, analytical standard

Not available outside of the UK & Ireland.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Scopoletin may be used as a reference standard for the determination of scopoletin in:Roots, stems, branches, and seeds as well as leaves of Chimonanthus nitens Oliv. by ultra-high performance liquid chromatography/tandem quadrupole-time-of-flight mass spectrometry (UHPLC-QTOF-MS/MS) equipped with modified mass deflect filter or diagnostic product ions/neutral loss filter.Canscora decussate (South Indian Shankhpushpi) extracts by high performance thin layer chromatography (HPTLC).Morinda tinctoria Roxb. leaf by HPTLC in conjunction with HPLC and gas chromatography with MS.

Biochem/physiol Actions

Scopoletin significantly increases activity of lipoprotein lipase in adipocytes by promoting transcription of the LPL gene. It also partially reverses inhibition of LPL by TNF-α.

General description

Scopoletin is a coumarin compound and pharmacologically active chemical that is found in various plant species.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.