Hydrate de sel désinfecté de sulfobromophtaléine, utilisé pour étudier les fonctions de transport de l'Hépatocyte

Code: s0252-5g D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Sulfobromophthalein disodium salt hydrate has been used as a positive control to study the interaction of 11-keto-β-boswellic acid (KBA) and 3-acetyl-11-keto-β-bo...


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Votre prix
$607.12 5G
Abandonné

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Sulfobromophthalein disodium salt hydrate has been used as a positive control to study the interaction of 11-keto-β-boswellic acid (KBA) and 3-acetyl-11-keto-β-boswellic acid (AKBA) with organic anion transporter OATP1B3.

Biochem/physiol Actions

Sulfobromophthalein (BSP) is a high affinity organic ion substrate for organic anion transporting polypeptides (OATPs) and has been used as a substrate for multidrug resistance associated protein 2 (Mrp2). BSP is transported into hepatocytes by OATPs and, after conjugation to glutathione, is excreted into bile by Mrp2. It was found to inhibit the aldo-keto reductase ARK1C20.

Packaging

5 g in glass bottle

application(s)diagnostic assay manufacturinghematologyhistology
InChI keyCDTNUNQQEUGDSD-UHFFFAOYSA-L
InChI1S/C20H10Br4O10S2.2Na.H2O/c21-15-13-14(16(22)18(24)17(15)23)20(34-19(13)27,7-1-3-9(25)11(5-7)35(28,29)30)8-2-4-10(26)12(6-8)36(31,32)33;;;/h1-6,25-26H,(H,28,29,30)(H,31,32,33);;;1H2/q;2*+1;/p-2
Quality Level200
SMILES string[Na+].[Na+].[H]O[H].Oc1ccc(cc1S([O-])(=O)=O)C2(OC(=O)c3c(Br)c(Br)c(Br)c(Br)c23)c4ccc(O)c(c4)S([O-])(=O)=O
solubilitywater: 50 mg/mL, clear to hazy
storage temp.room temp
Cas Number123359-42-2
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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