Pimelic Diphenylamide 106, >=98% (HPLC)

Code: sml0313-5mg D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

106 is a Class I HDAC inhibitor, demonstrating no activity against class II HDACs. It is a slow, tight-binding inhibitor of HDACs 1, 2, and 3, with a ...


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Your Price
$109.21 5MG

Not available outside of the UK & Ireland.

Biochem/physiol Actions

106 is a Class I HDAC inhibitor, demonstrating no activity against class II HDACs. It is a slow, tight-binding inhibitor of HDACs 1, 2, and 3, with a preference toward HDAC3 with Ki of 14 nM, 15 times lower than the Ki for HDAC1.

Pimelic diphenylamides has the ability to enhance the expression of the frataxin gene in lymphocytes from Friedreich ataxia patients.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyWTKBRPXPNAKVEQ-UHFFFAOYSA-N
InChI1S/C20H25N3O2/c1-15-11-13-16(14-12-15)22-19(24)9-3-2-4-10-20(25)23-18-8-6-5-7-17(18)21/h5-8,11-14H,2-4,9-10,21H2,1H3,(H,22,24)(H,23,25)
Quality Level100
SMILES stringCc1ccc(NC(=O)CCCCCC(=O)Nc2ccccc2N)cc1
solubilityDMSO: ≥15 mg/mL
storage temp.2-8°C
Cas Number937039-45-7
This product has met the following criteria to qualify for the following awards:



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