Pilocarpine nitrate salt, >=98% (TLC), powder

Code: p6628-10g D2-231

Not available outside of the UK & Ireland.

Application

Pilocarpine nitrate salt has been used to measure bronchoconstriction and M2 and M3 muscarinic receptor function in vivo. It has also been used to induce electrog...


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$216.74 10G
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Not available outside of the UK & Ireland.

Application

Pilocarpine nitrate salt has been used to measure bronchoconstriction and M2 and M3 muscarinic receptor function in vivo. It has also been used to induce electrographic and behavioral seizures and to study the different patterns of neuronal activation and neurodegeneration in Proechimys rats and Wistar rats.

Biochem/physiol Actions

Pilocarpine is a cholinergic muscarinic agonist, useful in inducing epilepsy in animal models. It is specially used to study the pathogenesis of epileptogenesis and pharmacoresistant epilepsy. Pilocarpine application is more popular among the rat and mice models.

Nonselective muscarinic acetylcholine receptor agonist; used to produce an experimental model of epilepsy.

assay≥98% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)
InChI keyPRZXEPJJHQYOGF-GNAZCLTHSA-N
InChI1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1
optical activity[α]25/D +83°, c = 10 in H2O(lit.)
Quality Level100
SMILES stringO[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C
solubilityH2O: 100 mg/mL
Cas Number148-72-1
Hazard Class6.1
Un Number2811
Pack GroupII
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