Myriocin from Mycelia sterilia, >=98% (HPLC), powder

Code: m1177-5mg D2-231

Not available outside of the UK & Ireland.

Application

Myriocin from Mycelia sterilia has been used as an inhibitor of sphingolipid or ceramide biosynthesis in various studies.

Biochem/physiol A...


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Your Price
$148.08 5MG
REQUEST

Not available outside of the UK & Ireland.

Application

Myriocin from Mycelia sterilia has been used as an inhibitor of sphingolipid or ceramide biosynthesis in various studies.

Biochem/physiol Actions

Myriocin from Mycelia sterilia is a fungal metabolite with potent immunosuppressant activity. It inhibits serine palmitoyltransferase at picomolar concentrations blocking synthesis of ceramide, a precursor of sphingomyelin and glycosphingolipids. It disrupts substratum adhesion of melanoma cells. It has been suggested that its immunosuppressant activity in the cytotoxic T-cell line CTTL-2 is due to apoptosis induction.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
coloroff-white
formpowder
InChI keyZZIKIHCNFWXKDY-GNTQXERDSA-N
InChI1S/C21H39NO6/c1-2-3-4-10-13-17(24)14-11-8-6-5-7-9-12-15-18(25)19(26)21(22,16-23)20(27)28/h9,12,18-19,23,25-26H,2-8,10-11,13-16,22H2,1H3,(H,27,28)/b12-9+/t18-,19+,21+/m1/s1
Quality Level200
SMILES stringCCCCCCC(=O)CCCCCCC=CC[C@@H](O)[C@H](O)[C@@](N)(CO)C(O)=O
solubilitymethanol: 2 mg/mL
storage temp.2-8°C
Cas Number35891-70-4
Hazard Class6.1
Un Number2811
Pack GroupIII
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