Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
GSK2801 is a potent inhibitor of the BAZ2 family of bromodomain containing proteins. BAZ2A is an essential component of the nucleolar remodeling complex (NoRC), which mediates recruitment of histone modifying enzymes and DNA methylase involved in the silencing of ribosomal RNA transcription. BAZ2B is believed to be involved in regulating nucleosome mobilization along linear DNA. For full characterization details, please visit the GSK2801 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
Features and Benefits
GSK2801 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Other Notes
GSK2801 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the GSK2801 probe summary on the Chemical Probes Portal website.
Light sensitive
Packaging
5, 25 mg in glass bottle
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :