Not available outside of the UK & Ireland.
Biochem/physiol Actions
RORγ Activator 1b binds to the retinoid-related orphan receptor RORγ and induces IL-17 reporter gene expression with an EC50 of 0.1 µM. The compound RORγ Activator 1b enhances differentiation of CD4+ T cells to IL-17-secreting cells with a maximum effect of 220 percent of control at 3 µM.
Packaging
5, 25 mg in glass bottle
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