Loteprednol Etabonate, >=98% (HPLC)

Code: sml0547-50mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Loteprednol Etabonate is an anti-inflammatory corticosteroid (ophthalmology).

Loteprednol Etabonate is a "soft" steroid, typically used in topic...


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Votre prix
$450.98 50MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Loteprednol Etabonate is an anti-inflammatory corticosteroid (ophthalmology).

Loteprednol Etabonate is a "soft" steroid, typically used in topical applications for inflammatory conditions of the eye. Loteprednol Etabonate is an agonist of both glucocorticoid and mineralcorticoid receptors.

Loteprednol etabonate (LE) is a key site-active corticosteroid. It is produced by structural modifications of prednisolone-related compounds to form an inactive metabolite. Double-masked study states that loteprednol etabonate is used to treat giant papillary conjunctivitis, seasonal allergic conjunctivitis, postoperative inflammation and uveitis. LE has good ocular permeation properties.

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
Gene Informationhuman ... NR3C1(2908)
InChI keyDMKSVUSAATWOCU-HROMYWEYSA-N
InChI1S/C24H31ClO7/c1-4-30-21(29)32-24(20(28)31-13-25)10-8-17-16-6-5-14-11-15(26)7-9-22(14,2)19(16)18(27)12-23(17,24)3/h7,9,11,16-19,27H,4-6,8,10,12-13H2,1-3H3/t16-,17-,18-,19+,22-,23-,24-/m0/s1
Quality Level100
SMILES stringCCOC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]12C)C(=O)OCCl
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.−20°C
Cas Number82034-46-6
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