SB265610, >=98% (HPLC)

Code: SML0421-5MG D2-231

Not available outside of the UK & Ireland.

Application

SB265610 has been used:as a cysteine-amino acid-cysteine (CXC)-chemokine receptor type 2 (CXCR2) antagonist to study its effects on the binding of chemokine with ...


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Your Price
$185.78 5MG
REQUEST

Not available outside of the UK & Ireland.

Application

SB265610 has been used:as a cysteine-amino acid-cysteine (CXC)-chemokine receptor type 2 (CXCR2) antagonist to study its effects on the binding of chemokine with G-protein coupled receptors (GPCR)as a CX-chemokine receptor type 1 (CXCR1) inhibitor to study its effect on the chemotactic activity of chemokines on inflammatory cellsas a CXCR2 antagonist to study its effect on migration of neutrophils to the rat brain

Biochem/physiol Actions

SB265610 is a potent and selective CXCR2 chemokine receptor antagonist. It has a Kd = 2.5 nM.

Features and Benefits

This compound is featured on the Chemokine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to light brown
formpowder
InChI keySEDUMQWZEOMXSO-UHFFFAOYSA-N
InChI1S/C14H9BrN6O/c15-9-3-1-2-4-10(9)17-14(22)18-11-6-5-8(7-16)12-13(11)20-21-19-12/h1-6H,(H2,17,18,22)(H,19,20,21)
Quality Level100
SMILES stringBrc1ccccc1NC(=O)Nc2ccc(C#N)c3nn[nH]c23
solubilityDMSO: 15 mg/mL, clear
storage temp.2-8°C
Cas Number211096-49-0
This product has met the following criteria to qualify for the following awards:



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