Kartogenin, >=98% (HPLC)

Code: SML0370-25MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Kartogenin is a small heterocyclic compound. It is involved in regulating runt-related transcription factor 1 (RUNX1), which plays an important role i...


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$527.71 25MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

Kartogenin is a small heterocyclic compound. It is involved in regulating runt-related transcription factor 1 (RUNX1), which plays an important role in chondrocyte proliferation and survival.

Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes. Kartogenin binds to filamin A, and disrupts the specific interaction between filamin A and CBFβ (core-binding factor β subunit). Apparently, kartogenin induces chondrogenesis by regulating the nuclear localization of CBFβ.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
formpowder
InChI keySLUINPGXGFUMLL-UHFFFAOYSA-N
InChI1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
Quality Level100
SMILES stringO=C(NC1=CC=C(C2=CC=CC=C2)C=C1)C(C=CC=C3)=C3C(O)=O
solubilityDMSO: >15 mg/mL
storage temp.room temp
Cas Number4727-31-5
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